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N Engl J Med. 2012 Aug 30;367(9):817-25. doi: 10.1056/NEJMoa1204133. Effects of clopidogrel added to aspirin in patients with recent lacunar stroke. In patients undergoing percutaneous coronary intervention and in those with acute coronary syndromes, clopidogrel plus aspirin is the first-line antiplatelet ...

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The effectiveness of clopidogrel bisulfate is dependent on its activation to an active metabolite by the cytochrome P450 (CYP) system, principally CYP2C19 [ see ... DESCRIPTION. PLAVIX (clopidogrel bisulfate) is an inhibitor of ADP-induced platelet aggregation acting by direct inhibition of adenosine diphosphate (ADP) ...

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Evaluation of prasugrel compared with clopidogrel in patients with acute coronary syndromes: design and rationale for the TRial to assess Improvement in ... Clopidogrel can cause side effects, although serious reactions are rare. Jan 24, 2012 ... Plavix (clopidogrel bisulfate) tablets Drug SAfety Label CHanges August 2010. Aug 30, 2012 ... Original Article from The New England Journal of Medicine — Effects of Clopidogrel Added to Aspirin in Patients with Recent Lacunar Stroke. clopidogrel patient information. Detailed drug information for the consumer, includes dosage, clopidogrel side effects and more. Sep 5, 2012 ... Objectives To estimate the clinical effectiveness associated with clopidogrel treatment after myocardial infarction (MI) in patients with diabetes. clopidogrel antiplatelet mechanism of action
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